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1

Multilineage communication regulates human liver bud development from pluripotency

Camp, J. Gray, Sekine, Keisuke, Gerber, Tobias, Loeffler-Wirth, Henry, Binder, Hans, Gac, Malgorzata, Kanton, Sabina, Kageyama, Jorge, Damm, Georg, Seehofer, Daniel, Belicova, Lenka, Bickle, Marc, Bar

Journal:

Year:

2017

Language:

english

File:

PDF, 16.04 MB

english, 2017

2

The beautiful cell: high-content screening in drug discovery

Journal:

Analytical and Bioanalytical Chemistry

Year:

2010

Language:

english

File:

PDF, 141 KB

english, 2010

3

Selection and characterization of large collections of peptide aptamers through optimized yeast two-hybrid procedures

Bickle, Marc B T, Dusserre, Eric, Moncorgé, Olivier, Bottin, Hélène, Colas, Pierre

Journal:

Nature Protocols

Year:

2006

Language:

english

File:

PDF, 659 KB

english, 2006

4

Inhibition of vaccinia virus replication by peptide aptamers

Laurent Saccucci, Jean-Marc Crance, Pierre Colas, Marc Bickle, Daniel Garin, Frédéric Iseni

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 503 KB

english, 2009

5

Immune system development during early childhood in tropical Latin America: Evidence for the age-dependent down regulation of the innate immune response

Rommy Teran, Edward Mitre, Maritza Vaca, Silvia Erazo, Gisela Oviedo, Marc P. Hübner, Martha E. Chico, Joseph J. Mattapallil, Quentin Bickle, Laura C. Rodrigues, Philip J. Cooper

Journal:

Clinical Immunology

Year:

2011

Language:

english

File:

PDF, 559 KB

english, 2011

6

The Yeast Phosphatidylinositol Kinase Homolog TOR2 Activates RHO1 and RHO2 via the Exchange Factor ROM2

Anja Schmidt, Marc Bickle, Thomas Beck, Michael N Hall

Journal:

Year:

1997

Language:

english

File:

PDF, 4.23 MB

english, 1997

7

Integration of Chemical and RNAi Multiparametric Profiles Identifies Triggers of Intracellular Mycobacterial Killing

Sundaramurthy, Varadharajan, Barsacchi, Rico, Samusik, Nikolay, Marsico, Giovanni, Gilleron, Jerome, Kalaidzidis, Inna, Meyenhofer, Felix, Bickle, Marc, Kalaidzidis, Yannis, Zerial, Marino

Journal:

Cell Host & Microbe

Year:

2013

Language:

english

File:

PDF, 2.30 MB

english, 2013

8

A Conserved RhoGAP Limits M Phase Contractility and Coordinates with Microtubule Asters to Confine RhoA during Cytokinesis

Zanin, Esther, Desai, Arshad, Poser, Ina, Toyoda, Yusuke, Andree, Cordula, Moebius, Claudia, Bickle, Marc, Conradt, Barbara, Piekny, Alisa, Oegema, Karen

Journal:

Developmental Cell

Year:

2013

Language:

english

File:

PDF, 5.09 MB

english, 2013

9

Erratum to: Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model

Borg, Danielle J., Weigelt, Marc, Wilhelm, Carmen, Gerlach, Michael, Bickle, Marc, Speier, Stephan, Bonifacio, Ezio, Hommel, Angela

Journal:

Year:

2014

Language:

english

File:

PDF, 152 KB

english, 2014

10

Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model

Borg, Danielle J., Weigelt, Marc, Wilhelm, Carmen, Gerlach, Michael, Bickle, Marc, Speier, Stephan, Bonifacio, Ezio, Hommel, Angela

Journal:

Year:

2014

Language:

english

File:

PDF, 704 KB

english, 2014

11

Deducing the mechanism of action of compounds identified in phenotypic screens by integrating their multiparametric profiles with a reference genetic screen

Sundaramurthy, Varadharajan, Barsacchi, Rico, Chernykh, Mikhail, Stöter, Martin, Tomschke, Nadine, Bickle, Marc, Kalaidzidis, Yannis, Zerial, Marino

Journal:

Nature Protocols

Year:

2014

Language:

english

File:

PDF, 916 KB

english, 2014

12

3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions

Wenzel, Carsten, Riefke, Björn, Gründemann, Stephan, Krebs, Alice, Christian, Sven, Prinz, Florian, Osterland, Marc, Golfier, Sven, Räse, Sebastian, Ansari, Nariman, Esner, Milan, Bickle, Marc, Pampal

Journal:

Experimental Cell Research

Year:

2014

Language:

english

File:

PDF, 3.07 MB

english, 2014

13

Systems drug discovery: a quantitative, objective approach for safer drug development

Journal:

Expert Opinion on Drug Discovery

Year:

2012

Language:

english

File:

PDF, 171 KB

english, 2012

14

Proliferating versus differentiating stem and cancer cells exhibit distinct midbody-release behaviour

Ettinger, Andreas W., Wilsch-Bräuninger, Michaela, Marzesco, Anne-Marie, Bickle, Marc, Lohmann, Annett, Maliga, Zoltan, Karbanová, Jana, Corbeil, Denis, Hyman, Anthony A., Huttner, Wieland B.

Journal:

Nature Communications

Year:

2011

Language:

english

File:

PDF, 1.73 MB

english, 2011

15

Image Analysis in High Content Screening

Niederlein, Antje, Meyenhofer, Felix, White, Daniel, Bickle, Marc

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2009

Language:

english

File:

PDF, 143 KB

english, 2009

16

Screening out irrelevant cell-based models of disease

Horvath, Peter, Aulner, Nathalie, Bickle, Marc, Davies, Anthony M., Nery, Elaine Del, Ebner, Daniel, Montoya, Maria C., Östling, Päivi, Pietiäinen, Vilja, Price, Leo S., Shorte, Spencer L., Turcatti,

Journal:

Nature Reviews Drug Discovery

Year:

2016

Language:

english

File:

PDF, 614 KB

english, 2016

17

SLAS Europe High-Content Screening Conference in Dresden

Montoya, Maria, Dorval, Thierry, Bickle, Marc

Journal:

Journal of Biomolecular Screening

Year:

2016

Language:

english

File:

PDF, 396 KB

english, 2016

18

Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation

Carthy, Jon M., Stöter, Martin, Bellomo, Claudia, Vanlandewijck, Michael, Heldin, Angelos, Morén, Anita, Kardassis, Dimitris, Gahman, Timothy C., Shiau, Andrew K., Bickle, Marc, Zerial, Marino, Heldin

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 7.01 MB

english, 2016

19

Gender, Contraceptives and Individual Metabolic Predisposition Shape a Healthy Plasma Lipidome

Sales, Susanne, Graessler, Juergen, Ciucci, Sara, Al-Atrib, Rania, Vihervaara, Terhi, Schuhmann, Kai, Kauhanen, Dimple, Sysi-Aho, Marko, Bornstein, Stefan R., Bickle, Marc, Cannistraci, Carlo V., Ekro

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.00 MB

english, 2016

20

Protective efficacy of phosphodiesterase-1 inhibition against alpha-synuclein toxicity revealed by compound screening in LUHMES cells

Höllerhage, Matthias, Moebius, Claudia, Melms, Johannes, Chiu, Wei-Hua, Goebel, Joachim N., Chakroun, Tasnim, Koeglsperger, Thomas, Oertel, Wolfgang H., Rösler, Thomas W., Bickle, Marc, Höglinger, Gün

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 5.92 MB

english, 2017

21

Layer-by-Layer assembly of heparin and peptide-polyethylene glycol conjugates to form hybrid nanothin films of biomatrices

Thomas, Alvin Kuriakose, Wieduwild, Robert, Zimmermann, Ralf, Lin, Weilin, Friedrichs, Jens, Bickle, Marc, Fahmy, Karim, Werner, Carsten, Zhang, Yixin

Journal:

ACS Applied Materials & Interfaces

Year:

2018

Language:

english

File:

PDF, 1.47 MB

english, 2018

22

A RasGAP SH3 Peptide Aptamer Inhibits RasGAP-Aurora Interaction and Induces Caspase-Independent Tumor Cell Death

Pamonsinlapatham, Perayot, Hadj-Slimane, Réda, Raynaud, Françoise, Bickle, Marc, Corneloup, Claudine, Barthelaix, Audrey, Lepelletier, Yves, Mercier, Perrine, Schapira, Matthieu, Samson, Jérôme, Mathi

Journal:

Year:

2008

Language:

english

File:

PDF, 657 KB

english, 2008

23

Concerns, challenges and promises of high-content analysis of 3D cellular models

Carragher, Neil, Piccinini, Filippo, Tesei, Anna, Jr, O. Joseph Trask, Bickle, Marc, Horvath, Peter

Journal:

Nature Reviews Drug Discovery

Year:

2018

Language:

english

File:

PDF, 137 KB

english, 2018

24

Phenotype loss is associated with widespread divergence of the gene regulatory landscape in evolution

Roscito, Juliana G., Sameith, Katrin, Parra, Genis, Langer, Bjoern E., Petzold, Andreas, Moebius, Claudia, Bickle, Marc, Rodrigues, Miguel Trefaut, Hiller, Michael

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 1.34 MB

english, 2018

25

Protein Methyltransferase Inhibition Decreases Endocrine Specification Through the Upregulation of Aldh1b1 Expression

Giannios, Ioannis, Serafimidis, Ioannis, Anastasiou, Vivian, Pezzolla, Daniela, Lesche, Mathias, Andree, Cordula, Bickle, Marc, Gavalas, Anthony

Journal:

Year:

2019

File:

PDF, 1.54 MB

2019

26

Unbiased Phenotype Detection Using Negative Controls

Janosch, Antje, Kaffka, Carolin, Bickle, Marc

Journal:

Year:

2019

Language:

english

File:

PDF, 366 KB

english, 2019

27

The Academic Pill: How Academia Contributes to Curing Diseases

Journal:

Year:

2019

File:

PDF, 139 KB

2019

28

Unbiased Screens for Modifiers of Alpha-Synuclein Toxicity

Höllerhage, Matthias, Bickle, Marc, Höglinger, Günter U.

Journal:

Current Neurology and Neuroscience Reports

Year:

2019

Language:

english

File:

PDF, 1.38 MB

english, 2019

29

The Academic Pill: How Academia Contributes to Curing Diseases

Journal:

Year:

2019

Language:

english

File:

PDF, 139 KB

english, 2019

30

Viral Infections Exacerbate FUS-ALS Phenotypes in iPSC-Derived Spinal Neurons in a Virus Species-Specific Manner

Bellmann, Jessica, Monette, Anne, Tripathy, Vadreenath, Sójka, Anna, Abo-Rady, Masin, Janosh, Antje, Bhatnagar, Rajat, Bickle, Marc, Mouland, Andrew J., Sterneckert, Jared

Journal:

Frontiers in Cellular Neuroscience

Year:

2019

File:

PDF, 6.74 MB

2019

31

Knocking out C9ORF72 Exacerbates Axonal Trafficking Defects Associated with Hexanucleotide Repeat Expansion and Reduces Levels of Heat Shock Proteins

Abo-Rady, Masin, Kalmbach, Norman, Pal, Arun, Schludi, Carina, Janosch, Antje, Richter, Tanja, Freitag, Petra, Bickle, Marc, Kahlert, Anne-Karin, Petri, Susanne, Stefanov, Stefan, Glass, Hannes, Staeg

Journal:

Stem Cell Reports

Year:

2020

Language:

english

File:

PDF, 3.27 MB

english, 2020

32

A Human Retinal Pigment Epithelium-Based Screening Platform Reveals Inducers of Photoreceptor Outer Segments Phagocytosis

Schreiter, Sven, Vafia, Katerina, Barsacchi, Rico, Tsang, Stephen H., Bickle, Marc, Ader, Marius, Karl, Mike O., Tanaka, Elly M., Almedawar, Seba

Journal:

Stem Cell Reports

Year:

2020

File:

PDF, 5.01 MB

2020